… Heredity (Edinb). Virulence-associated gene profiling of Streptococcus suis isolates by PCR. Lempp C, Spitzbarth I, Puff C, Cana A, Kegler K, Techangamsuwan S, Baumgärtner W, Seehusen F. Viruses. Institut für Pathologie, Tierärztliche Hochschule Hannover, Bischofsholer Damm 15, D‐3000 Hannover 1Search for more papers by this author. Publication History. 2005 Oct;110(4):369-82. doi: 10.1007/s00401-005-1055-z. Would you like email updates of new search results? Likewise, MMPs and TIMPs are prominently up-regulated in these lesions and are expressed mostly by astrocytes and microglia. 2019 Feb;122(2):172-186. doi: 10.1038/s41437-018-0090-1. Gutachter: Univ.-Prof. Marion Hewicker-Trautwein und PD Dr. med. Thus, intravenous application of this serotype 9 strain is required to evaluate heterologous protection in the course of vaccine development based on serotype 2 strains in the future. Tierärztliche Hochschule Hannover Population and molecular genetic analyses of persistent right aortic arch and primary cataracts in the German Pinscher INAUGURAL-DISSERTATION zur Erlangung des Grades einer Doktorin der Veterinärmedizin - Doctor medicinae veterinariae – (Dr. med. 2016 Jul;11:941-54. doi: 10.2217/fmb-2016-0028. Shen M, Di G, Li M, Fu J, Dai Q, Miao X, Huang M, You W, Ke C. Sci Rep. 2018 Apr 19;8(1):6269. doi: 10.1038/s41598-018-24645-z.  |  In acute and subacute CDE, a plaque-associated CD44 up-regulation is found that parallels astrocyte activation. Due to the central nervous system (CNS) tropism of the virus and associated neuropathological changes, demyelinating canine distemper encephalitis (CDE) represents a relevant model for human demyelinating diseases like multiple sclerosis.  |   |  2009 Dec 15;132(2-4):135-45. doi: 10.1016/j.vetimm.2009.05.009. Project: Effects of habitat fragmentation on parasite communities in mouse lemurs (Microcebus spp.) 2003 Nov;106(5):486-94. doi: 10.1007/s00401-003-0754-6. 6 Kliniken, 19 Institute, 3 Fachgebiete und 3 Außenstellen gehören zur Stiftung Tierärztliche Hochschule Hannover. Institut für Pathologie, Tierärztliche Hochschule Hannover, Bünteweg 17, D‐3000 Hannover 71, Germany . : 0511 / 953-8621 , 0511 / 953-8664 Diagnostik-Sprechstunden: Mo. (2)Institut für Pathologie, Stiftung Tierärztliche Hochschule Hannover. 2000 Feb;99(2):138-46. doi: 10.1007/pl00007417. Gregor Warnecke Institut für Herz-, Thorax-, Transplantations- und Gefäßchirurgie Medizinische Hochschule Hannover 1. Uncovering newly emerging variants of Streptococcus suis, an important zoonotic agent. This site needs JavaScript to work properly. Institute of Microbiology and Infectious Diseases of Animals, School of Veterinary Medicine, Hannover, Germany. We are a leader in research, teaching and services in veterinary medicine and train young scientists in all areas of veterinary science. 2020 Jul 25;21(15):5289. doi: 10.3390/ijms21155289. Hannover und Umgebung, Deutschland Scientific Assistant at the Institute for Experimental Pathology of the Medical School Hannover (Director: Professor Dr. U. Mohr). NLM NLM Dr. med. Clipboard, Search History, and several other advanced features are temporarily unavailable. Toward Understanding the Genetic Basis of Yak Ovary Reproduction: A Characterization and Comparative Analyses of Estrus Ovary Transcriptiome in Yak and Cattle. doi: 10.1371/journal.pone.0152675. (3)Zentrum für Systemische Neurowissenschaften Hannover, ZSN. Further Information. COVID-19 is an emerging, rapidly evolving situation. See 3 photos and 3 tips from 80 visitors to Tierärztliche Hochschule Hannover. vet.) Fragen der Diagnostik: Geschäftszimmer, Tel.-Nr. Experimental intranasal and intravenous infections of 7-8 weeks old SPF piglets were investigated with regard to clinic and pathology. Tenenbaum T, Asmat TM, Seitz M, Schroten H, Schwerk C. Future Microbiol. eCollection 2016. Comparative mRNA and miRNA expression in European mouflon (Ovis musimon) and sheep (Ovis aries) provides novel insights into the genetic mechanisms for female reproductive success. J. Willemse N, van der Ark KCH, Stockhofe-Zurwieden N, Smith H, Picavet DI, van Solt-Smits C, Wisselink HJ, Schultsz C, de Greeff A. Sci Rep. 2019 Oct 28;9(1):15429. doi: 10.1038/s41598-019-51576-0. PLoS One. 2020 May 6;6:12. doi: 10.1186/s40813-020-00150-6. PLoS One. Studies on pathogenesis as well as vaccine trials have focused on serotype 2 strains, which are worldwide the most prevalent among invasive isolates. Andrea Düngelhoef, Sophie Gschaider, Jana Seele, Nadine Büttner, and Christoph Hirche are acknowledged for their excellent work during their practicals. In summary, CD44 and MMPs might be associated with the onset of demyelination and may interact to initiate ECM disturbances. (1)Institut für Pathologie, Tierärztliche Hochschule Hannover, 30559 Hannover, Germany. Meurer M, Öhlmann S, Bonilla MC, Valentin-Weigand P, Beineke A, Hennig-Pauka I, Schwerk C, Schroten H, Baums CG, Köckritz-Blickwede MV, de Buhr N. Int J Mol Sci. A 5-year-old German-Holstein cow was presented with a swelling of the head which had been present for 3 months. Andreas Beineke Institut für Pathologie Tierärztliche Hochschule Hannover Prof. Dr. med.  |  Research topics. Beyerbach (Stiftung Tierärztliche Hochschule Hannover, Hannover, Germany) kindly provided support in statistical analysis. This page... Print this page. G. Trautwein. 2019 Oct 10;3:100046. doi: 10.1016/j.jvacx.2019.100046. Clinical manifestations related to meningitis, arthritis and serositis could be induced by intravenous application of this serotype 9 strain. Epub 2003 Aug 15. Porcine Health Manag. Ziel dieser Arbeit war es, festzustellen, ob und wann eine PCV 2-Infektion vor 1998, dem Jahr des erstmaligen Nachweises von PCV 2 in Deutschland, im Sektionsmaterial des Instituts für Pathologie der Stiftung Tierärztliche Hochschule Hannover aufgetreten ist. Rieckmann K, Seydel A, Klose K, Alber G, Baums CG, Schütze N. Vaccine X. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. Epub 2005 Aug 25. Save as PDF. Would you like email updates of new search results? The present review decribes the role of CD44 antigen (CD44), the principle cell surface receptor for hyaluronate and extracellular matrix (ECM) processing enzymes (matrix metalloproteinases [MMPs]) and their inhibitors (TIMPs) in the pathogenesis of demyelination. Zhao ZQ, Wang LJ, Sun XW, Zhang JJ, Zhao YJ, Na RS, Zhang JH. 2009 Nov 18;139(3-4):310-7. doi: 10.1016/j.vetmic.2009.06.024. NIH Pathogenesis and immunopathology of systemic and nervous canine distemper. Friederike Döring: Die intrazelluläre Lokalisation von Isoformen des Fibroblastenwachstumsfaktors – 2 (FGF-2). Biological activities of suilysin: role in Streptococcus suis pathogenesis. Please enable it to take advantage of the complete set of features! andreas.beineke@tiho-hannover.de Harbor porpoises from the North and Baltic Seas exhibit a higher incidence of bacterial infections compared to whales from less polluted arctic waters. (1)Institut für Pathologie, Stiftung Tierärztliche Hochschule Hannover, Hannover, Germany. Ligation of CD44 in the early phase may induce chemokines and cytokines and hence initiate and perpetuate the inflammatory process. 2016 Apr 4;11(4):e0152675.  |  Up-regulation of the hyaluronate receptor CD44 in canine distemper demyelinated plaques. In this phase, a decrease of MMP and TIMP expressions apart from MMP-11, -12, and -13 is obvious. HHS D-30559 Hannover, Germany e-mail: Send e-mail . Epub 2009 Jun 21. However, in Europe serotype 9 strains also contribute substantially to S. suis-associated invasive diseases of piglets. The program is subdivided into different seminars (modules) and receives support from speakers from Pharmaceutical and Chemical companies mainly located in Germany. Institut für Pathologie, Tierärztliche Hochschule Hannover, Peter Wohlsein. NCI CPTC Antibody Characterization Program. 2014 Jul 2;6(7):2571-601. doi: 10.3390/v6072571. Interestingly, expression of MRP within meningitis lesions was demonstrated for both pathotypes via immunohistochemistry. 2009 Jan 15;127(1-2):1-18. doi: 10.1016/j.vetimm.2008.09.023. It is often referred to as TiHo by its staff and students. vet. The working group „Behavioural ecology and conservation genetics“ aims to understand the factors, that drive and influence the evolution of social structures, the demographic composition, ecological niche construction, distribution, connectivity and the survival of populations. In contrast to the virulent serotype 2 strain, the serotype 9 strain did not cause disease with clinical manifestations after intranasal administration. Prevention and treatment information (HHS). However, histological screenings of these animals revealed pathological lesions, such as mild focal suppurative meningitis. "Perfect place to start a veterinary career" To study the interactions between probiotic micro-organisms and the host their effects on morphology and mucins of the intestinal mucosa were investigated. 1 Institut für Pathologie, Tierärztliche Hochschule Hannover, Germany. Institut für Mikrobiologie und Tierseucben Direktor: Prof. Dr. W. Bisping der Tierärztlichen Hochschule Hannover Tierärztliche Hochschule, 3 Hannover, Bischofsholer Damm 15. Institut für Pathologie Tierärztliche Hochschule Hannover PD Dr. med.  |  NIH Gutachten: Prof. Dr. med. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. (3)3 Institut für Pathologie der Stiftung Tieraerztliche Hochschule Hannover, Hannover, Germany. Carlos Hermosilla Institut für Parasitologie Beineke A, Puff C, Seehusen F, Baumgärtner W. Vet Immunol Immunopathol. Corresponding Author. Please enable it to take advantage of the complete set of features! Epub 2017 Nov 28. PMID: 12016561 DOI: 10.1055/s-2002-30116 Abstract The mode of action of probiotics is still incompletely understood. 2010 Mar;18(3):124-31. doi: 10.1016/j.tim.2009.12.003. Author information: (1)Klinik für Rinder, Stiftung Tierärztliche Hochschule Hannover. Stiftung Tierärztliche Hochschule Hannover. Streptococcus (S.) suis is an invasive porcine pathogen causing meningitis, septicemia, arthritis and other diseases. Epub 2018 May 21. Zusammenfassung. Gregor Warnecke 2. COVID-19 is an emerging, rapidly evolving situation. Mol Med Rep. 2018 Feb;17(2):2161-2168. doi: 10.3892/mmr.2017.8177. Alldinger S, Fonfara S, Kremmer E, Baumgärtner W. Acta Neuropathol. Search Google Scholar for this author, R. Müller-Peddinghaus. (4)4 Klinik für Heimtiere, Reptilien, Zier- und Wildvoegel, Stiftung Tieraerztliche Hochschule, Hannover… Centre National des Listeria, Institut de Microbiologie, CHUV, CH‐19 Sud 1011, Lausanne, Switzerland . Kock C, Beineke A, Seitz M, Ganter M, Waldmann KH, Valentin-Weigand P, Baums CG. Clinical examination revealed a 15 × 20 × 15 cm firm … This site needs JavaScript to work properly. eCollection 2015. 2015 Mar 30;10(3):e0121586. Arwid Daugschies Institut für Parasitologie Veterinärmedizinische Fakultät der Universität Leipzig 2. Institut für Pathologie der Tierärztlichen Hochschule Hannover, Bünteweg 17, D‐3000 Hannover 71, Germany. Donhauser & Schöneberger, Bingen am Rhein, Germany. Bibliografische Informationen der Deutschen Bibliothek Die Deutsche Bibliothek verzeichnet diese Publikation in der Deutschen Nationalbibliografie; Detaillierte bibliografische Da In conclusion, this study demonstrates that MRP* SLY+ serotype 9 strains are less virulent for growers than MRP+ EF+ SLY+ serotype 2 strains. Institute of Pathology, Section of Immunopathology and Institute of Virology, School of Veterinary Medicine, Hannover. Center for Systems Neuroscience, Stiftung Tierärztliche Hochschule Hannover, Medizinische Hochschule Hannover, ... Bedeutung für die molekulare Pathologie der Spinalen Muskelatrophie. Epub 2008 Oct 4. 2 Institut für Pathologie, Stiftung Tierärztliche Hochschule Hannover, M. Ganter. Office: Phone: 0049-(0)511- 953-8621; 0049-(0)511-953-8664 Fax: 0049-(0)511-953-8675 Diagnostic service section - consultation hours: Monday – Friday from 2.30 pm – 4.30 pm; phone: 0049-(0)511-953-8622 Aerial photography: Department of Pathology. eCollection 2020. Role of Bacterial and Host DNases on Host-Pathogen Interaction during, A critical review speculating on the protective efficacies of autogenous, From Stable to Lab-Investigating Key Factors for Sudden Deaths Caused by, Vaccination with the immunoglobulin M-degrading enzyme of. The skin lesions were divided into four macroscopic groups: scaling (group I, n = 5), hyperkeratotic and hyperplastic plaque‐like lesions (group II, n = 14), nodular skin masses (group III, n = 16) and verrucous skin lesions (group IV, n = 2). Aerial photography: Department of Pathology. Proteomics Studies on the three Larval Stages of Development and Metamorphosis of Babylonia areolata. (2)2 Tieraerztliche Gemeinschaftspraxis Dres. eCollection 2019 Dec 10. vet. Institut für Pathologie, Tierärztliche Hochschule Hannover › Author Affiliations › Further Information. 1 Klinik für kleine Klauentiere, forensische Medizin und Ambulatorische Klinik, Stiftung Tierärztliche Hochschule Hannover › Author Affiliations. Stiftung Tierärztliche Hochschule Hannover. In chronic lesions, CD44 expression declines together with the number of glial fibrillary acidic protein (GFAP) positive astrocytes. Silva LM, Baums CG, Rehm T, Wisselink HJ, Goethe R, Valentin-Weigand P. Vet Microbiol. Abteilung für Experimentelle Pathologie, Dr. Karl Thomae GmbH, Biberach/Riß, und Institut für Pathologie, Abteilung für Immunpathologie, Tierärztliche Hochschule Hannover, Hannover, BRD See all articles by this author. Doctoral student . vet. Hennig-Pauka I, Imker R, Mayer L, Brügmann M, Werckenthin C, Weber H, Menrath A, de Buhr N. Pathogens. Yang J, Li X, Cao YH, Pokharel K, Hu XJ, Chen ZH, Xu SS, Peippo J, Honkatukia M, Kantanen J, Li MH. Stiftung Tierärztliche Hochschule Hannover. Intranasal immunization with a live Streptococcus suis isogenic ofs mutant elicited suilysin-neutralization titers but failed to induce opsonizing antibodies and protection. Epub 2016 Jun 30. Abstract; Full Text; References Buy Article Permissions and Reprints. Stiftung Tierärztliche Hochschule Hannover. New aspects of the pathogenesis of canine distemper leukoencephalitis. The University of Veterinary Medicine Hanover (German: Tierärztliche Hochschule Hannover, TiHo) is a university in Hanover and one of the five facilities for veterinary medicine in Germany, and the only one that remains independent. Microarray analysis reveals gene and microRNA signatures in diabetic kidney disease. TiHo Hannover - Institut für Pathologie Toxicologic Pathology Training Program A comprehensive Toxicologic Pathology Program is offered within the residency program of the TiHo. 2006 Jun 15;115(1-3):117-27. doi: 10.1016/j.vetmic.2005.12.013. Canine distemper virus (CDV) belongs to the genus Morbillivirus of the Paramyxoviridae family. HHS Clipboard, Search History, and several other advanced features are temporarily unavailable. Corresponding Author. Transcriptome analysis of the Capra hircus ovary. Bacteriological culture and immunohistochemistry of the brain confirmed association with the S. suis challenge strains in all cases with clinical manifestations. The principal histological findings were hyperkeratosis and epidermal hyperplasia. Phase-dependent expression of matrix metalloproteinases and their inhibitors in demyelinating canine distemper encephalitis. Rieckmann K, Pendzialek SM, Vahlenkamp T, Baums CG. R. Müller-Peddinghaus . Vet Immunol Immunopathol. A. Navarro Camarro. Search for more papers by this author. Clonal expansion of a virulent Streptococcus suis serotype 9 lineage distinguishable from carriage subpopulations. Epub 2010 Jan 12. Fittipaldi N, Fuller TE, Teel JF, Wilson TL, Wolfram TJ, Lowery DE, Gottschalk M. Vet Microbiol. In addition, in this plaque type, CD44 is expressed on the cell membrane of perivascular mononuclear cells. The University of Veterinary Medicine Hannover, Foundation (TiHo) is a nationally and internationally recognized institution of higher education known for its excellence in veterinary science and its interdisciplinary focus. Corresponding Author . Dr. med. vorgelegt von Julia Menzel Stuttgart Hannover 2010 . Prevention and treatment information (HHS). Up-regulation of mRNA for matrix metalloproteinases-9 and -14 in advanced lesions of demyelinating canine distemper leukoencephalitis. Institut für Pathologie, Tierärztliche Hochschule Hannover, FRG. USA.gov. 2019 Nov 20;8(4):249. doi: 10.3390/pathogens8040249. Streptococcus (S.) suis is an invasive porcine pathogen causing meningitis, septicemia, arthritis and other diseases. Serotype distribution and production of muramidase-released protein, extracellular factor and suilysin by field strains of Streptococcus suis isolated in the United States. in northwestern Madagasca. Universität Hannover, 2007. Medizinische Hochschule Hannover, 2006. USA.gov. (1)Institut für Pathologie, Stiftung Tierärztliche Hochschule Hannover, D-30173 Hannover, Germany. Search for more papers by this author. doi: 10.1371/journal.pone.0121586. Epub 2006 Jan 20. Trends Microbiol. Institut für Pathologie, Tierärztliche Hochschule, Bunteweg 17, D‐30559 Hannover, Germany. Epub 2009 May 18. Acta Neuropathol. In the chronic phase, it is conceivable that a MMP-TIMP imbalance may be the motor for lesion progression with a simultaneous influx of CD44-positive activated immune cells. Tierärztliche Hochschule Hannover Prof. Dr. med. The objective of this study was to determine the virulence of an MRP* SLY+ serotype 9 S. suis strain in comparison to an MRP+ EF+ SLY+ serotype 2 strain. University Overview Founded in 1778, Tierärztliche Hochschule Hannover (University of Veterinary Medicine Hannover) is a non-profit public higher-education institution located in the urban setting of the large city of Hannover (population range of 500,000-1,000,000 inhabitants), Lower Saxony. J. Pohlenz. Miao Q, Baumgärtner W, Failing K, Alldinger S. Acta Neuropathol.
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